Free Fall Force Spectroscopy of Nebulin Suggests Improved Folding after Repeated Stretching

Altered reflex sensitivity after repeated and prolonged passive muscle stretching.

Experiments were carried out to test the effect of prolonged and repeated passive stretching (RPS) of the triceps surae muscle on reflex sensitivity. The results demonstrated a clear deterioration of muscle function immediately after RPS. Maximal voluntary contraction, average electromyographic activity of the gastrocnemius and soleus muscles, and zero crossing rate of the soleus muscle (record...

Stretching Folding Instablility and Nanoemulsion

Stretching lattice models of protein folding.

A new class of experiments that probe folding of individual protein domains uses mechanical stretching to cause the transition. We show how stretching forces can be incorporated in lattice models of folding. For fast folding proteins, the analysis suggests a complex relation between the force dependence and the reaction coordinate for folding.

Separating stretching from folding in fluid mixing

Fluid mixing controls many natural and industrial processes, including the spread of air pollution1, mass transfer and reactions in microfluidic devices2,3 and the detection of odours or other chemical signals4. Strongly nonlinear flows enhance mixing by chaotic advection5,6, stretching and folding7,8 fluid volumes. Though these processes have been studied in simple models9,10, stretching and f...

Stretching and folding in finite time.

Complex flows mix efficiently, and this process can be understood by considering the stretching and folding of material volumes. Although many metrics have been devised to characterize stretching, fewer are able to capture folding in a quantitative way in spatiotemporally variable flows. Here, we extend our previous methods based on the finite-time curving of fluid-element trajectories to nonze...